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Hypermarker's Background

What is hypertension?

Hypertension, or high blood pressure, is not a disease but a risk factor for various serious health conditions.

 

It involves consistently elevated blood pressure, which strains the heart, blood vessels, and organs.

 

Hypertension increases the risk of conditions like heart disease, stroke, kidney disease, and vision loss by damaging blood vessels. Over time, this damage can lead to serious complications, such as heart attack and stroke.

What are the risks associated with hypertension?

  • Heart disease

  • Kidney damage

  • Brain damage

  • Vision loss

  • Aneurysm

  • Atherosclerosis

Why is hypertension medication ineffective at times?

  • People's non-adherence to medication

  • Resistance to medication

  • Lifestyle factors

  • Interactions with other medications

  • Undiagnosed secondary causes

  • Genetic factors

Metabolomics

Metabolomics is the study of all the small molecules (metabolites) in a biological sample, such as blood or tissue, and how they change in response to various stimuli, such as diseases, environmental factors, or treatments. By analysing the metabolome, scientists can gain insights into the biological processes taking place in a living organism and how they're affected by various factors.

Pharmacometabolomics

Pharmacometabolomics, a subfield of pharmacology and metabolomics, studies how drugs and other therapeutic interventions impact an individual's metabolic profile. 

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By using pharmacometabolomics, healthcare providers can gain a fuller picture of how a patient's individual metabolic profile impacts their response to treatment and develop personalised treatment plans that take this into account.

 

This can help improve the efficacy and safety of treatments and reduce the risk of adverse reactions. 

Companion diagnostics

Companion diagnostics are medical tests used alongside specific treatments to identify suitable candidates based on genetic and biological traits. 

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They help identify patients who harbour specific genetic mutations for better treatment outcomes, avoiding those less likely to respond positively to the treatment. 

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Companion diagnostics enable personalised treatment, enhancing outcomes and minimising side effects for better patient success.

What's the effect of hypertension on healthcare costs?

Hypertension significantly drives up healthcare expenses, particularly due to its key role in cardiovascular disease.

 

Costs encompass direct medical bills and indirect expenses, like reduced productivity and quality of life.

 

These costs stem form increase hospitalisations, lifelong medication, cardiovascular diseases, and kidney problems associated with hypertension.

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